Topical Mitomycin as an Adjunct to Choanal Atresia Repair

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Topical mitomycin as an adjunct to choanal atresia repair.

OBJECTIVE To evaluate the use of topical mitomycin in choanal atresia repair to reduce the development of granulation tissue and cicatrix. DESIGN AND SETTING Retrospective case series in 2 tertiary care centers. PATIENTS Twenty patients with either unilateral or bilateral congenital choanal atresia underwent repair using the transnasal endoscopic approach, the transpalatal approach, or both...

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Surgical management of choanal atresia: improved outcome using mitomycin.

OBJECTIVE To evaluate the intraoperative use of mitomycin to improve the surgical outcome and reduce the rate of soft tissue restenosis in children undergoing choanal atresia repair. DESIGN Retrospective chart review of all patients surgically treated for congenital choanal atresia by the senior author (W.F.M). SETTING Tertiary children's hospital. PATIENTS Eight consecutive patients with...

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Evaluation of topical bevacizumab as an adjunct to mitomycin C augmented trabeculectomy

PURPOSE To investigate the safety and synergistic effect of topical bevacizumab after trabeculectomy surgery with mitomycin C (MMC). METHODS In this prospective, non-randomized, comparative interventional study, 40 eyes from 40 patients with uncontrolled open-angle glaucoma were studied after they underwent primary trabeculectomy with mitomycin C (0.02% for 2 min). Following the procedure top...

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Choanal atresia.

Choanal atresia is caused by failure of resorption of the bucco-pharyngeal membrane during embryonic development. The atresia can be membranous or bony in nature, but is usually mixed in most cases. When the atresia is bilateral, newborns can have severe airway distress and cyanosis is alleviated by crying. Bilateral choanal atresia is managed with an oropharyngeal airway. Flexible nasal endosc...

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Bilateral choanal atresia in an adult - management with mitomycin C and without stents: a case report

BACKGROUND A 23-year-old female patient presented to the outpatient clinic with bilateral nasal obstruction and discharge since birth. Endoscopic examination and paranasal sinus tomography revealed bilateral choanal atresia. She did not have any other congenital abnormalities. Her parents reported cyanosis in childhood that worsened during feeding and improved during crying; however, they had n...

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ژورنال

عنوان ژورنال: Archives of Otolaryngology–Head & Neck Surgery

سال: 2002

ISSN: 0886-4470

DOI: 10.1001/archotol.128.4.398